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Notch and retinoic acid signals regulate macrophage formation from endocardium downstream of Nkx2-5
Hematopoietic progenitors are enriched in the endocardial cushion and contribute, in a Nkx2-5-dependent manner, to tissue macrophages required for the remodeling of cardiac valves and septa. However, little is known about the molecular mechanism of endocardial-hematopoietic transition. In the curren...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480477/ https://www.ncbi.nlm.nih.gov/pubmed/37669937 http://dx.doi.org/10.1038/s41467-023-41039-6 |