KCC2 reverse mode helps to clear postsynaptically released potassium at glutamatergic synapses

Extracellular potassium [K(+)](o) elevation during synaptic activity retrogradely modifies presynaptic release and astrocytic uptake of glutamate. Hence, local K(+) clearance and replenishment mechanisms are crucial regulators of glutamatergic transmission and plasticity. Based on recordings of astr...

Descripción completa

Detalles Bibliográficos
Autores principales: Byvaltcev, Egor, Behbood, Mahraz, Schleimer, Jan-Hendrik, Gensch, Thomas, Semyanov, Alexey, Schreiber, Susanne, Strauss, Ulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480490/
https://www.ncbi.nlm.nih.gov/pubmed/37537840
http://dx.doi.org/10.1016/j.celrep.2023.112934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480490/
https://www.ncbi.nlm.nih.gov/pubmed/37537840
http://dx.doi.org/10.1016/j.celrep.2023.112934

Ejemplares similares