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KCC2 reverse mode helps to clear postsynaptically released potassium at glutamatergic synapses
Extracellular potassium [K(+)](o) elevation during synaptic activity retrogradely modifies presynaptic release and astrocytic uptake of glutamate. Hence, local K(+) clearance and replenishment mechanisms are crucial regulators of glutamatergic transmission and plasticity. Based on recordings of astr...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480490/ https://www.ncbi.nlm.nih.gov/pubmed/37537840 http://dx.doi.org/10.1016/j.celrep.2023.112934 |