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MtrA modulates Mycobacterium tuberculosis cell division in host microenvironments to mediate intrinsic resistance and drug tolerance

The success of Mycobacterium tuberculosis (Mtb) is largely attributed to its ability to physiologically adapt and withstand diverse localized stresses within host microenvironments. Here, we present a data-driven model (EGRIN 2.0) that captures the dynamic interplay of environmental cues and genome-...

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Detalles Bibliográficos
Autores principales: Peterson, Eliza J.R., Brooks, Aaron N., Reiss, David J., Kaur, Amardeep, Do, Julie, Pan, Min, Wu, Wei-Ju, Morrison, Robert, Srinivas, Vivek, Carter, Warren, Arrieta-Ortiz, Mario L., Ruiz, Rene A., Bhatt, Apoorva, Baliga, Nitin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480492/
https://www.ncbi.nlm.nih.gov/pubmed/37542718
http://dx.doi.org/10.1016/j.celrep.2023.112875