Box Behnken optimization of cubosomes for enhancing the anticancer activity of metformin: Design, characterization, and in-vitro cell proliferation assay on MDA-MB-231 breast and LOVO colon cancer cell lines

This study aimed to formulate and statistically optimize cubosomal formulations of metformin (MTF) to enhance its breast anticancer activity. A Box Behnken design was employed using Design-Expert® software. The formulation variables were glyceryl monooleate concentration (GMO) w/w%, Pluronic F-127 c...

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Detalles Bibliográficos
Autores principales: Zaki, Randa Mohammed, Alkharashi, Layla A., Sarhan, Omnia M., Almurshedi, Alanood S., Aldosari, Basmah Nasser, Said, Mayada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480553/
https://www.ncbi.nlm.nih.gov/pubmed/37680878
http://dx.doi.org/10.1016/j.ijpx.2023.100208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480553/
https://www.ncbi.nlm.nih.gov/pubmed/37680878
http://dx.doi.org/10.1016/j.ijpx.2023.100208

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