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The fading guardian: clinical relevance of TP53 null mutation in high-grade serous ovarian cancers

BACKGROUND: we evaluated the concordance between immunohistochemical p53 staining and TP53 mutations in a series of HGSOC. Moreover, we searched for prognostic differences between p53 overexpression and null expression groups. METHODS: patients affected by HGSOC were included. For each case p53 immu...

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Detalles Bibliográficos
Autores principales: Biatta, Chiara M., Paudice, Michele, Greppi, Marco, Parrella, Veronica, Parodi, Alessia, De Luca, Giuseppa, Cerruti, Gianna Maria, Mammoliti, Serafina, Caroti, Cinzia, Menichini, Paola, Fronza, Gilberto, Pesce, Silvia, Marcenaro, Emanuela, Vellone, Valerio G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480567/
https://www.ncbi.nlm.nih.gov/pubmed/37680633
http://dx.doi.org/10.3389/fimmu.2023.1221605