Inhibition of nonsense-mediated mRNA decay reduces the tumorigenicity of human fibrosarcoma cells

Nonsense-mediated mRNA decay (NMD) is a eukaryotic RNA decay pathway with roles in cellular stress responses, differentiation, and viral defense. It functions in both quality control and post-transcriptional regulation of gene expression. NMD has also emerged as a modulator of cancer progression, al...

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Detalles Bibliográficos
Autores principales: Nasif, Sofia, Colombo, Martino, Uldry, Anne-Christine, Schröder, Markus S, de Brot, Simone, Mühlemann, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Cancer Gene Regulation, Chromatin, and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480688/
https://www.ncbi.nlm.nih.gov/pubmed/37681034
http://dx.doi.org/10.1093/narcan/zcad048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480688/
https://www.ncbi.nlm.nih.gov/pubmed/37681034
http://dx.doi.org/10.1093/narcan/zcad048

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