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Inhibition of nonsense-mediated mRNA decay reduces the tumorigenicity of human fibrosarcoma cells
Nonsense-mediated mRNA decay (NMD) is a eukaryotic RNA decay pathway with roles in cellular stress responses, differentiation, and viral defense. It functions in both quality control and post-transcriptional regulation of gene expression. NMD has also emerged as a modulator of cancer progression, al...
Autores principales: | Nasif, Sofia, Colombo, Martino, Uldry, Anne-Christine, Schröder, Markus S, de Brot, Simone, Mühlemann, Oliver |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480688/ https://www.ncbi.nlm.nih.gov/pubmed/37681034 http://dx.doi.org/10.1093/narcan/zcad048 |
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