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Zebrafish functional xenograft vasculature platform identifies PF-502 as a durable vasculature normalization drug

Tumor vasculature often exhibits disorder and inefficiency. Vascular normalization offers potential for alleviating hypoxia and optimizing drug delivery in tumors. However, identifying effective agents is hindered by a lack of robust screening. We aimed to establish a comprehensive method using the...

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Detalles Bibliográficos
Autores principales: Zhong, Jian, Xiao, Chaoxin, Chen, Qin, Pan, Xiangyu, Xu, Tongtong, Wang, Yiyun, Hou, Wanting, Liu, Lu, Cao, Fujun, Wang, Yulin, Li, Xiaoying, Zhou, Lin, Yang, Hanshuo, Yang, Yu, Zhao, Chengjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480778/
https://www.ncbi.nlm.nih.gov/pubmed/37680473
http://dx.doi.org/10.1016/j.isci.2023.107734