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SARS-CoV-2 Nsp15 suppresses type I interferon production by inhibiting IRF3 phosphorylation and nuclear translocation

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes 2019 coronavirus disease (COVID-19), poses a significant threat to global public health security. Like other coronaviruses, SARS-CoV-2 has developed various strategies to inhibit the production of interferon (IFN). Here, we h...

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Detalles Bibliográficos
Autores principales: Zhang, Dianqi, Ji, Likai, Chen, Xu, He, Yumin, Sun, Yijie, Ji, Li, Zhang, Tiancheng, Shen, Quan, Wang, Xiaochun, Wang, Yan, Yang, Shixing, Zhang, Wen, Zhou, Chenglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480782/
https://www.ncbi.nlm.nih.gov/pubmed/37680466
http://dx.doi.org/10.1016/j.isci.2023.107705