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Sex-Biased T-cell Exhaustion Drives Differential Immune Responses in Glioblastoma

Sex differences in glioblastoma (GBM) incidence and outcome are well recognized, and emerging evidence suggests that these extend to genetic/epigenetic and cellular differences, including immune responses. However, the mechanisms driving immunologic sex differences are not fully understood. Here, we...

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Detalles Bibliográficos
Autores principales: Lee, Juyeun, Nicosia, Michael, Hong, Ellen S., Silver, Daniel J., Li, Cathy, Bayik, Defne, Watson, Dionysios C., Lauko, Adam, Kay, Kristen E., Wang, Sabrina Z., Johnson, Sadie, McGraw, Mary, Grabowski, Matthew M., Kish, Danielle D., Desai, Amar B., Goodman, Wendy A., Cameron, Scott J., Okada, Hideho, Valujskikh, Anna, Fairchild, Robert L., Ahluwalia, Manmeet S., Lathia, Justin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481130/
https://www.ncbi.nlm.nih.gov/pubmed/37378557
http://dx.doi.org/10.1158/2159-8290.CD-22-0869