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The circular RNA Ataxia Telangiectasia Mutated regulates oxidative stress in smooth muscle cells in expanding abdominal aortic aneurysms

An abdominal aortic aneurysm (AAA) is a pathological widening of the aortic wall characterized by loss of smooth muscle cells (SMCs), extracellular matrix degradation, and local inflammation. This condition is often asymptomatic until rupture occurs, leading to high morbidity and mortality rates. Di...

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Detalles Bibliográficos
Autores principales: Fasolo, Francesca, Winski, Greg, Li, Zhaolong, Wu, Zhiyan, Winter, Hanna, Ritzer, Julia, Glukha, Nadiya, Roy, Joy, Hultgren, Rebecka, Pauli, Jessica, Busch, Albert, Sachs, Nadja, Knappich, Christoph, Eckstein, Hans-Henning, Boon, Reinier A., Paloschi, Valentina, Maegdefessel, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481153/
https://www.ncbi.nlm.nih.gov/pubmed/37680984
http://dx.doi.org/10.1016/j.omtn.2023.08.017