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Lobaplatin induces apoptosis in T24 and 5637 bladder cancer cells by regulating Bcl-2 and Bax expression and inhibiting the PI3K/Akt signaling pathway

BACKGROUND: Lobaplatin (LBP) is a third-generation platinum-based drug that has been approved only in China for the treatment of several cancer types. Nonetheless, its efficacy in treating bladder cancer (BC) is unclear thus far. Through in vitro and in vivo experiments, this study aimed to explore...

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Detalles Bibliográficos
Autores principales: Yu, Qian, Lan, Tianwei, Ma, Zhina, Wang, Zhanlei, Zhang, Chunmei, Jiang, Yichuan, Zhao, Zhongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481196/
https://www.ncbi.nlm.nih.gov/pubmed/37680227
http://dx.doi.org/10.21037/tau-23-376