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Design, synthesis, X-ray crystal structures, anticancer, DNA binding, and molecular modelling studies of pyrazole–pyrazoline hybrid derivatives

We have designed and synthesized three pyrazole analogs (4, 5a, 5b), pyrazole-based chalcones (6a–6d) and (8a–8h), and N-formyl/acetyl 1,3,5-trisubstituted pyrazoline analogs (7a–7d), (9a–9d). FT-IR, (1)H, (13)C NMR, and mass spectrometry techniques were used to describe the structures of all the sy...

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Detalles Bibliográficos
Autores principales: Rana, Manish, Hungyo, Hungharla, Parashar, Palak, Ahmad, Shaban, Mehandi, Rabiya, Tandon, Vibha, Raza, Khalid, Assiri, Mohammed A., Ali, Tarik E., El-Bahy, Zeinhom M., Rahisuddin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481259/
https://www.ncbi.nlm.nih.gov/pubmed/37681049
http://dx.doi.org/10.1039/d3ra04873j