Fluid shear stress-modulated chromatin accessibility reveals the mechano-dependency of endothelial SMAD1/5-mediated gene transcription

Bone morphogenetic protein (BMP) signaling and fluid shear stress (FSS) mediate complementary functions in vascular homeostasis and disease development. It remains to be shown whether altered chromatin accessibility downstream of BMP and FSS offers a crosstalk level to explain changes in SMAD-depend...

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Detalles Bibliográficos
Autores principales: Jatzlau, Jerome, Mendez, Paul-Lennard, Altay, Aybuge, Raaz, Lion, Zhang, Yufei, Mähr, Sophia, Sesver, Akin, Reichenbach, Maria, Mundlos, Stefan, Vingron, Martin, Knaus, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481294/
https://www.ncbi.nlm.nih.gov/pubmed/37680470
http://dx.doi.org/10.1016/j.isci.2023.107405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481294/
https://www.ncbi.nlm.nih.gov/pubmed/37680470
http://dx.doi.org/10.1016/j.isci.2023.107405

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