Exendin-4 promotes retinal ganglion cell survival and function by inhibiting calcium channels in experimental diabetes

Progressive damage of retinal ganglion cells (RGCs) is observed in early diabetic retinopathy. Intracellular Ca(2+) overload mediated by Ca(2+) influx through voltage-gated Ca(2+) channels (VGCCs) is involved in neurodegeneration, whereas glucagon-like peptide-1 (GLP-1) provides neuroprotection. How...

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Detalles Bibliográficos
Autores principales: Wang, Yong-Chen, Wang, Lu, Shao, Yu-Qi, Weng, Shi-Jun, Yang, Xiong-Li, Zhong, Yong-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481356/
https://www.ncbi.nlm.nih.gov/pubmed/37680468
http://dx.doi.org/10.1016/j.isci.2023.107680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481356/
https://www.ncbi.nlm.nih.gov/pubmed/37680468
http://dx.doi.org/10.1016/j.isci.2023.107680

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