Cargando…

Allosteric modulation of cytochrome P450 enzymes by the NADPH cytochrome P450 reductase FMN-containing domain

NADPH-cytochrome P450 reductase delivers electrons required by heme oxygenase, squalene monooxygenase, fatty acid desaturase, and 48 human cytochrome P450 enzymes. While conformational changes supporting reductase intramolecular electron transfer are well defined, intermolecular interactions with th...

Descripción completa

Detalles Bibliográficos
Autores principales: Burris-Hiday, Sarah D., Scott, Emily E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481364/
https://www.ncbi.nlm.nih.gov/pubmed/37517692
http://dx.doi.org/10.1016/j.jbc.2023.105112