Integrative analysis of single-cell RNA-seq and ATAC-seq reveals heterogeneity of induced pluripotent stem cell-derived hepatic organoids

To gain deeper insights into transcriptomes and epigenomes of organoids, liver organoids from two states (expandable and more differentiated) were subjected to single-cell RNA-seq (scRNA-seq) and single-cell ATAC-seq (scATAC-seq) analyses. Mitochondrial gene expression was higher in differentiated t...

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Detalles Bibliográficos
Autores principales: Kim, Jong-Hwan, Mun, Seon Ju, Kim, Jeong-Hwan, Son, Myung Jin, Kim, Seon-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481365/
https://www.ncbi.nlm.nih.gov/pubmed/37680467
http://dx.doi.org/10.1016/j.isci.2023.107675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481365/
https://www.ncbi.nlm.nih.gov/pubmed/37680467
http://dx.doi.org/10.1016/j.isci.2023.107675

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