Lysozyme–Sucrose Interactions in the Solid State: Glass Transition, Denaturation, and the Effect of Residual Water

[Image: see text] The freeze-drying of proteins, along with excipients, offers a solution for increasing the shelf-life of protein pharmaceuticals. Using differential scanning calorimetry, thermogravimetric analysis, sorption calorimetry, and synchrotron small-angle X-ray scattering (SAXS), we have...

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Detalles Bibliográficos
Autores principales: Bogdanova, Ekaterina, Lages, Sebastian, Phan-Xuan, Tuan, Kamal, Md. Arif, Terry, Ann, Millqvist Fureby, Anna, Kocherbitov, Vitaly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481396/
https://www.ncbi.nlm.nih.gov/pubmed/37555640
http://dx.doi.org/10.1021/acs.molpharmaceut.3c00403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481396/
https://www.ncbi.nlm.nih.gov/pubmed/37555640
http://dx.doi.org/10.1021/acs.molpharmaceut.3c00403

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