Inhibition of the SREBP pathway prevents SARS-CoV-2 replication and inflammasome activation

SARS-CoV-2 induces major cellular lipid rearrangements, exploiting the host’s metabolic pathways to replicate. Sterol regulatory element binding proteins (SREBPs) are a family of transcription factors that control lipid metabolism. SREBP1 is associated with the regulation of fatty acids, whereas SRE...

Descripción completa

Detalles Bibliográficos
Autores principales: Soares, Vinicius Cardoso, Dias, Suelen Silva Gomes, Santos, Julia Cunha, Azevedo-Quintanilha, Isaclaudia G, Moreira, Isabela Batista Gonçalves, Sacramento, Carolina Q, Fintelman-Rodrigues, Natalia, Temerozo, Jairo R, da Silva, Marcos Alexandre Nunes, Barreto-Vieira, Debora Ferreira, Souza, Thiago ML, Bozza, Patricia T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481517/
https://www.ncbi.nlm.nih.gov/pubmed/37669865
http://dx.doi.org/10.26508/lsa.202302049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481517/
https://www.ncbi.nlm.nih.gov/pubmed/37669865
http://dx.doi.org/10.26508/lsa.202302049

Ejemplares similares