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Inhibition of the SREBP pathway prevents SARS-CoV-2 replication and inflammasome activation

SARS-CoV-2 induces major cellular lipid rearrangements, exploiting the host’s metabolic pathways to replicate. Sterol regulatory element binding proteins (SREBPs) are a family of transcription factors that control lipid metabolism. SREBP1 is associated with the regulation of fatty acids, whereas SRE...

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Detalles Bibliográficos
Autores principales:	Soares, Vinicius Cardoso, Dias, Suelen Silva Gomes, Santos, Julia Cunha, Azevedo-Quintanilha, Isaclaudia G, Moreira, Isabela Batista Gonçalves, Sacramento, Carolina Q, Fintelman-Rodrigues, Natalia, Temerozo, Jairo R, da Silva, Marcos Alexandre Nunes, Barreto-Vieira, Debora Ferreira, Souza, Thiago ML, Bozza, Patricia T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481517/ https://www.ncbi.nlm.nih.gov/pubmed/37669865 http://dx.doi.org/10.26508/lsa.202302049

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