Differential impact of 5-lipoxygenase-activating protein antagonists on the biosynthesis of leukotrienes and of specialized pro-resolving mediators

Lipoxygenases (LOX) transform arachidonic acid (AA, C20:4) and docosahexaenoic acid (DHA, C22:6) into bioactive lipid mediators (LMs) that comprise not only pro-inflammatory leukotrienes (LTs) but also the specialized pro-resolving mediators (SPMs) that promote inflammation resolution and tissue reg...

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Detalles Bibliográficos
Autores principales: Dahlke, Philipp, Peltner, Lukas K., Jordan, Paul M., Werz, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481534/
https://www.ncbi.nlm.nih.gov/pubmed/37680719
http://dx.doi.org/10.3389/fphar.2023.1219160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481534/
https://www.ncbi.nlm.nih.gov/pubmed/37680719
http://dx.doi.org/10.3389/fphar.2023.1219160

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