Generation and characterization of a zebrafish knockout model of abcb4, a homolog of the human multidrug efflux transporter P-glycoprotein

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The ATP-binding cassette subfamily B member 1 (ABCB1), encoding a multidrug transporter referred to as P-glycoprotein (Pgp), plays a critical role in the efflux of xenobiotics in humans and is implicated in cancer resistance to chemotherapy. Therefore, developing high-throughput animal models to scr...

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Detalles Bibliográficos
Autores principales: Park, Jinhee, Kim, Hyosung, Alabdalla, Leen, Mishra, Smriti, Mchaourab, Hassane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481557/
https://www.ncbi.nlm.nih.gov/pubmed/37674192
http://dx.doi.org/10.1186/s40246-023-00530-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481557/
https://www.ncbi.nlm.nih.gov/pubmed/37674192
http://dx.doi.org/10.1186/s40246-023-00530-3

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