Molecular profiling of pre- and post-treatment pediatric high-grade astrocytomas reveals acquired increased tumor mutation burden in a subset of recurrences

Diffuse gliomas are a heterogeneous category of primary central nervous system tumors. Due to their infiltrative growth precluding complete surgical resection, most diffuse high-grade gliomas are treated with adjuvant chemotherapy and radiation. Recurrent/progressive diffuse gliomas may show genetic...

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Detalles Bibliográficos
Autores principales: Wood, Matthew D., Beadling, Carol, Neff, Tanaya, Moore, Steve, Harrington, Christina A., Baird, Lissa, Corless, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481558/
https://www.ncbi.nlm.nih.gov/pubmed/37670377
http://dx.doi.org/10.1186/s40478-023-01644-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481558/
https://www.ncbi.nlm.nih.gov/pubmed/37670377
http://dx.doi.org/10.1186/s40478-023-01644-4

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