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Cantharidin induces apoptosis of human triple negative breast cancer cells through mir-607-mediated downregulation of EGFR

BACKGROUND: Triple negative breast cancer (TNBC) is a major subtype of breast cancer, with limited therapeutic drugs in clinical. Epidermal growth factor receptor (EGFR) is reported to be overexpressed in various TNBC cells. Cantharidin is an effective ingredient in many clinical traditional Chinese...

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Detalles Bibliográficos
Autores principales: Yang, Tianfeng, Yu, Runze, Cheng, Cheng, Huo, Jian, Gong, Zhengyan, Cao, Hanbing, Hu, Yu, Dai, Bingling, Zhang, Yanmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481602/
https://www.ncbi.nlm.nih.gov/pubmed/37670360
http://dx.doi.org/10.1186/s12967-023-04483-y