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Macrophage migration inhibitory factor exacerbates asthmatic airway remodeling via dynamin-related protein 1-mediated autophagy activation

BACKGROUND: Macrophage migration inhibitory factor (MIF) and GTPase dynamin-related protein 1 (Drp1)-dependent aberrant mitochondrial fission are closely linked to the pathogenesis of asthma. However, it is unclear whether Drp1-mediated mitochondrial fission and its downstream targets mediate MIF-in...

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Detalles Bibliográficos
Autores principales: Liu, Jin, Chen, Yuqian, Chen, Huan, Wang, Yan, Li, Danyang, Zhang, Qianqian, Chai, Limin, Qiu, Yuanjie, Zhang, Jia, Shen, Nirui, Wang, Qingting, Wang, Jian, Li, Manxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481618/
https://www.ncbi.nlm.nih.gov/pubmed/37674165
http://dx.doi.org/10.1186/s12931-023-02526-y