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RNA polymerase II CTD is dispensable for transcription and required for termination in human cells

The largest subunit of RNA polymerase (Pol) II harbors an evolutionarily conserved C‐terminal domain (CTD), composed of heptapeptide repeats, central to the transcriptional process. Here, we analyze the transcriptional phenotypes of a CTD‐Δ5 mutant that carries a large CTD truncation in human cells....

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Detalles Bibliográficos
Autores principales: Yahia, Yousra, Pigeot, Alexia, El Aabidine, Amal Zine, Shah, Nilay, Karasu, Nezih, Forné, Ignasi, Krebs, Stefan, Blum, Helmut, Esnault, Cyril, Sexton, Tom, Imhof, Axel, Eick, Dirk, Andrau, Jean‐Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481650/
https://www.ncbi.nlm.nih.gov/pubmed/37424514
http://dx.doi.org/10.15252/embr.202256150