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Terminal differentiation of villus tip enterocytes is governed by distinct Tgfβ superfamily members

The protective and absorptive functions of the intestinal epithelium rely on differentiated enterocytes in the villi. The differentiation of enterocytes is orchestrated by sub‐epithelial mesenchymal cells producing distinct ligands along the villus axis, in particular Bmps and Tgfβ. Here, we show th...

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Detalles Bibliográficos
Autores principales: Berková, Linda, Fazilaty, Hassan, Yang, Qiutan, Kubovčiak, Jan, Stastna, Monika, Hrckulak, Dusan, Vojtechova, Martina, Dalessi, Tosca, Brügger, Michael David, Hausmann, George, Liberali, Prisca, Korinek, Vladimir, Basler, Konrad, Valenta, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481656/
https://www.ncbi.nlm.nih.gov/pubmed/37493498
http://dx.doi.org/10.15252/embr.202256454