Cargando…

An ATG12‐ATG5‐TECPR1 E3‐like complex regulates unconventional LC3 lipidation at damaged lysosomes

Lysosomal membrane damage represents a threat to cell viability. As such, cells have evolved sophisticated mechanisms to maintain lysosomal integrity. Small membrane lesions are detected and repaired by the endosomal sorting complex required for transport (ESCRT) machinery while more extensively dam...

Descripción completa

Detalles Bibliográficos
Autores principales: Corkery, Dale P, Castro‐Gonzalez, Sergio, Knyazeva, Anastasia, Herzog, Laura K, Wu, Yao‐Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481663/
https://www.ncbi.nlm.nih.gov/pubmed/37381828
http://dx.doi.org/10.15252/embr.202356841