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Branched‐chain amino acid synthesis is coupled to TOR activation early in the cell cycle in yeast

How cells coordinate their metabolism with division determines the rate of cell proliferation. Dynamic patterns of metabolite synthesis during the cell cycle are unexplored. We report the first isotope tracing analysis in synchronous, growing budding yeast cells. Synthesis of leucine, a branched‐cha...

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Detalles Bibliográficos
Autores principales: Blank, Heidi M, Reuse, Carsten, Schmidt‐Hohagen, Kerstin, Hammer, Staci E, Hiller, Karsten, Polymenis, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481666/
https://www.ncbi.nlm.nih.gov/pubmed/37497662
http://dx.doi.org/10.15252/embr.202357372