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Apical bulkheads accumulate as adaptive response to impaired bile flow in liver disease

Hepatocytes form bile canaliculi that dynamically respond to the signalling activity of bile acids and bile flow. Little is known about their responses to intraluminal pressure. During embryonic development, hepatocytes assemble apical bulkheads that increase the canalicular resistance to intralumin...

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Detalles Bibliográficos
Autores principales: Mayer, Carlotta, Nehring, Sophie, Kücken, Michael, Repnik, Urska, Seifert, Sarah, Sljukic, Aleksandra, Delpierre, Julien, Morales‐Navarrete, Hernán, Hinz, Sebastian, Brosch, Mario, Chung, Brian, Karlsen, Tom, Huch, Meritxell, Kalaidzidis, Yannis, Brusch, Lutz, Hampe, Jochen, Schafmayer, Clemens, Zerial, Marino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481669/
https://www.ncbi.nlm.nih.gov/pubmed/37522754
http://dx.doi.org/10.15252/embr.202357181