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Apical bulkheads accumulate as adaptive response to impaired bile flow in liver disease
Hepatocytes form bile canaliculi that dynamically respond to the signalling activity of bile acids and bile flow. Little is known about their responses to intraluminal pressure. During embryonic development, hepatocytes assemble apical bulkheads that increase the canalicular resistance to intralumin...
Autores principales: | Mayer, Carlotta, Nehring, Sophie, Kücken, Michael, Repnik, Urska, Seifert, Sarah, Sljukic, Aleksandra, Delpierre, Julien, Morales‐Navarrete, Hernán, Hinz, Sebastian, Brosch, Mario, Chung, Brian, Karlsen, Tom, Huch, Meritxell, Kalaidzidis, Yannis, Brusch, Lutz, Hampe, Jochen, Schafmayer, Clemens, Zerial, Marino |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481669/ https://www.ncbi.nlm.nih.gov/pubmed/37522754 http://dx.doi.org/10.15252/embr.202357181 |
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