Targeting reversible post-translational modifications with PROTACs: a focus on enzymes modifying protein lysine and arginine residues

PROTACs represent an emerging field in medicinal chemistry, which has already led to the development of compounds that reached clinical studies. Posttranslational modifications contribute to the complexity of proteomes, with 2846 disease-associated sites. PROTAC field is very advanced in targeting k...

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Detalles Bibliográficos
Autores principales: Pichlak, Marta, Sobierajski, Tomasz, Błażewska, Katarzyna M., Gendaszewska-Darmach, Edyta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481767/
https://www.ncbi.nlm.nih.gov/pubmed/37667522
http://dx.doi.org/10.1080/14756366.2023.2254012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481767/
https://www.ncbi.nlm.nih.gov/pubmed/37667522
http://dx.doi.org/10.1080/14756366.2023.2254012

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