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Targeting reversible post-translational modifications with PROTACs: a focus on enzymes modifying protein lysine and arginine residues
PROTACs represent an emerging field in medicinal chemistry, which has already led to the development of compounds that reached clinical studies. Posttranslational modifications contribute to the complexity of proteomes, with 2846 disease-associated sites. PROTAC field is very advanced in targeting k...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481767/ https://www.ncbi.nlm.nih.gov/pubmed/37667522 http://dx.doi.org/10.1080/14756366.2023.2254012 |