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Discovery of new Schistosoma mansoni aspartyl protease inhibitors by structure-based virtual screening
BACKGROUND: Schistosomiasis is a neglected tropical disease caused by trematodes of the genus Schistosoma, with a limited treatment, mainly based on the use of praziquantel (PZQ). Currently, several aspartic proteases genes have already been identified within the genome of Schistosoma species. At le...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Instituto Oswaldo Cruz, Ministério da Saúde
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481938/ https://www.ncbi.nlm.nih.gov/pubmed/37672425 http://dx.doi.org/10.1590/0074-02760230031 |