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The loop-tail mouse model displays open and closed caudal neural tube defects

Neural tube defects (NTDs) are the second most common cause of congenital malformations and are often studied in animal models. Loop-tail (Lp) mice carry a mutation in the Vangl2 gene, a member of the Wnt-planar cell polarity pathway. In Vangl2(+/Lp) embryos, the mutation induces a failure in the co...

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Detalles Bibliográficos
Autores principales: Fernández-Santos, Beatriz, Reyes-Corral, Marta, Caro-Vega, José Manuel, Lao-Pérez, Miguel, Vallejo-Grijalba, Claudia, Mesa-Cruz, Cristina, Morón, Francisco J., Ybot-González, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481946/
https://www.ncbi.nlm.nih.gov/pubmed/37589570
http://dx.doi.org/10.1242/dmm.050175