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The loop-tail mouse model displays open and closed caudal neural tube defects
Neural tube defects (NTDs) are the second most common cause of congenital malformations and are often studied in animal models. Loop-tail (Lp) mice carry a mutation in the Vangl2 gene, a member of the Wnt-planar cell polarity pathway. In Vangl2(+/Lp) embryos, the mutation induces a failure in the co...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481946/ https://www.ncbi.nlm.nih.gov/pubmed/37589570 http://dx.doi.org/10.1242/dmm.050175 |