Disrupting Hedgehog signaling in melanocytes by SUFU knockout leads to ocular melanocytosis and anterior segment malformation

Hedgehog (Hh) signaling is well known for its crucial role during development, but its specific role in individual cell lineages is less well characterized. Here, we disrupted Hh signaling specifically in melanocytes by using Cre-mediated cell-type-specific knockout of the Hh regulator suppressor of...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Weizhuo, Li, Feiyang, Wang, Jing, Liu, Zuimeng, Tian, Meiyu, Wang, Zhenhang, Li, Huirong, Qu, Jia, Chen, Yu, Hou, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481947/
https://www.ncbi.nlm.nih.gov/pubmed/37577930
http://dx.doi.org/10.1242/dmm.050210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481947/
https://www.ncbi.nlm.nih.gov/pubmed/37577930
http://dx.doi.org/10.1242/dmm.050210

Ejemplares similares