Myeloid-specific blockade of notch signaling alleviates dopaminergic neurodegeneration in Parkinson’s disease by dominantly regulating resident microglia activation through NF-κB signaling

Yolk sac–derived microglia and peripheral monocyte–derived macrophages play a key role during Parkinson’s disease (PD) progression. However, the regulatory mechanism of microglia/macrophage activation and function in PD pathogenesis remains unclear. Recombination signal–binding protein Jκ (RBP-J)–me...

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Detalles Bibliográficos
Autores principales: Liang, Shi-Qian, Li, Peng-Hui, Hu, Yi-Yang, Zhao, Jun-Long, Shao, Fang-Ze, Kuang, Fang, Ren, Kai-Xi, Wei, Tiao-Xia, Fan, Fan, Feng, Lei, Han, Hua, Qin, Hong-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481959/
https://www.ncbi.nlm.nih.gov/pubmed/37680624
http://dx.doi.org/10.3389/fimmu.2023.1193081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10481959/
https://www.ncbi.nlm.nih.gov/pubmed/37680624
http://dx.doi.org/10.3389/fimmu.2023.1193081

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