Integrated signaling and transcriptome analysis reveals Src family kinase individualities and novel pathways controlled by their constitutive activity

The Src family kinases (SFKs) Lck and Lyn are crucial for lymphocyte development and function. Albeit tissue-restricted expression patterns the two kinases share common functions; the most pronounced one being the phosphorylation of ITAM motifs in the cytoplasmic tails of antigenic receptors. Lck is...

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Detalles Bibliográficos
Autores principales: Koutras, Nikolaos, Morfos, Vasileios, Konnaris, Kyriakos, Kouvela, Adamantia, Shaukat, Athanasios-Nasir, Stathopoulos, Constantinos, Stamatopoulou, Vassiliki, Nika, Konstantina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482094/
https://www.ncbi.nlm.nih.gov/pubmed/37680627
http://dx.doi.org/10.3389/fimmu.2023.1224520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482094/
https://www.ncbi.nlm.nih.gov/pubmed/37680627
http://dx.doi.org/10.3389/fimmu.2023.1224520

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