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Mechanistic insights into the biological activity of S-Sulfocysteine in CHO cells using a multi-omics approach

S-Sulfocysteine (SSC), a bioavailable L-cysteine derivative (Cys), is known to be taken up and metabolized in Chinese hamster ovary (CHO) cells used to produce novel therapeutic biological entities. To gain a deeper mechanistic insight into the SSC biological activity and metabolization, a multi-omi...

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Detalles Bibliográficos
Autores principales: Nguyen, Melanie, Le Mignon, Maxime, Schnellbächer, Alisa, Wehsling, Maria, Braun, Julian, Baumgaertner, Jens, Grabner, Martina, Zimmer, Aline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482334/
https://www.ncbi.nlm.nih.gov/pubmed/37680342
http://dx.doi.org/10.3389/fbioe.2023.1230422