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Rewiring the pneumococcal capsule pathway for investigating glycosyltransferase specificity and genetic glycoengineering

Virtually all living cells are covered with glycans. Their structures are primarily controlled by the specificities of glycosyltransferases (GTs). GTs typically adopt one of the three folds, namely, GT-A, GT-B, and GT-C. However, what defines their specificities remain poorly understood. Here, we de...

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Detalles Bibliográficos
Autores principales: Su, Tong, Chua, Wan-Zhen, Liu, Yao, Fan, Jingsong, Tan, Si-Yin, Yang, Dai-wen, Sham, Lok-To
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482335/
https://www.ncbi.nlm.nih.gov/pubmed/37672581
http://dx.doi.org/10.1126/sciadv.adi8157