Infection-experienced HSPCs protect against infections by generating neutrophils with enhanced mitochondrial bactericidal activity

Hematopoietic stem and progenitor cells (HSPCs) respond to infection by proliferating and generating in-demand neutrophils through a process called emergency granulopoiesis (EG). Recently, infection-induced changes in HSPCs have also been shown to underpin the longevity of trained immunity, where th...

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Detalles Bibliográficos
Autores principales: Darroch, Hannah, Keerthisinghe, Pramuk, Sung, Yih Jian, Rolland, Leah, Prankerd-Gough, Anneke, Crosier, Philip S., Astin, Jonathan W., Hall, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482338/
https://www.ncbi.nlm.nih.gov/pubmed/37672586
http://dx.doi.org/10.1126/sciadv.adf9904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482338/
https://www.ncbi.nlm.nih.gov/pubmed/37672586
http://dx.doi.org/10.1126/sciadv.adf9904

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