Nucleoside diphosphate kinases 1 and 2 regulate a protective liver response to a high-fat diet

The synthesis of fatty acids from acetyl–coenzyme A (AcCoA) is deregulated in diverse pathologies, including cancer. Here, we report that fatty acid accumulation is negatively regulated by nucleoside diphosphate kinases 1 and 2 (NME1/2), housekeeping enzymes involved in nucleotide homeostasis that w...

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Detalles Bibliográficos
Autores principales: Iuso, Domenico, Garcia-Saez, Isabel, Couté, Yohann, Yamaryo-Botté, Yoshiki, Boeri Erba, Elisabetta, Adrait, Annie, Zeaiter, Nour, Tokarska-Schlattner, Malgorzata, Jilkova, Zuzana Macek, Boussouar, Fayçal, Barral, Sophie, Signor, Luca, Couturier, Karine, Hajmirza, Azadeh, Chuffart, Florent, Bourova-Flin, Ekaterina, Vitte, Anne-Laure, Bargier, Lisa, Puthier, Denis, Decaens, Thomas, Rousseaux, Sophie, Botté, Cyrille, Schlattner, Uwe, Petosa, Carlo, Khochbin, Saadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482350/
https://www.ncbi.nlm.nih.gov/pubmed/37672589
http://dx.doi.org/10.1126/sciadv.adh0140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482350/
https://www.ncbi.nlm.nih.gov/pubmed/37672589
http://dx.doi.org/10.1126/sciadv.adh0140

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