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Repurposing the atypical type I-G CRISPR system for bacterial genome engineering
The CRISPR-Cas system functions as a prokaryotic immune system and is highly diverse, with six major types and numerous sub-types. The most abundant are type I CRISPR systems, which utilize a multi-subunit effector, Cascade, and a CRISPR RNA (crRNA) to detect invading DNA species. Detection leads to...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Microbiology Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482374/ https://www.ncbi.nlm.nih.gov/pubmed/37526970 http://dx.doi.org/10.1099/mic.0.001373 |