Repurposing anti-inflammatory drugs for fighting planktonic and biofilm growth. New carbazole derivatives based on the NSAID carprofen: synthesis, in silico and in vitro bioevaluation

INTRODUCTION: One of the promising leads for the rapid discovery of alternative antimicrobial agents is to repurpose other drugs, such as nonsteroidal anti-inflammatory agents (NSAIDs) for fighting bacterial infections and antimicrobial resistance. METHODS: A series of new carbazole derivatives base...

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Detalles Bibliográficos
Autores principales: Dumitrascu, Florea, Caira, Mino R., Avram, Speranta, Buiu, Catalin, Udrea, Ana Maria, Vlad, Ilinca Margareta, Zarafu, Irina, Ioniță, Petre, Nuță, Diana Camelia, Popa, Marcela, Chifiriuc, Mariana-Carmen, Limban, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482414/
https://www.ncbi.nlm.nih.gov/pubmed/37680749
http://dx.doi.org/10.3389/fcimb.2023.1181516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482414/
https://www.ncbi.nlm.nih.gov/pubmed/37680749
http://dx.doi.org/10.3389/fcimb.2023.1181516

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