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The ATM-E6AP-MASTL axis mediates DNA damage checkpoint recovery

Checkpoint activation after DNA damage causes a transient cell cycle arrest by suppressing cyclin-dependent kinases (CDKs). However, it remains largely elusive how cell cycle recovery is initiated after DNA damage. In this study, we discovered the upregulated protein level of MASTL kinase hours afte...

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Detalles Bibliográficos
Autores principales: Li, Yanqiu, Wang, Feifei, Li, Xin, Wang, Ling, Yang, Zheng, You, Zhongsheng, Peng, Aimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482428/
https://www.ncbi.nlm.nih.gov/pubmed/37672026
http://dx.doi.org/10.7554/eLife.86976