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Coordination between ECM and cell-cell adhesion regulates the development of islet aggregation, architecture, and functional maturation

Pancreatic islets are three-dimensional cell aggregates consisting of unique cellular composition, cell-to-cell contacts, and interactions with blood vessels. Cell aggregation is essential for islet endocrine function; however, it remains unclear how developing islets establish aggregation. By combi...

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Detalles Bibliográficos
Autores principales: Tixi, Wilma, Maldonado, Maricela, Chang, Ya-Ting, Chiu, Amy, Yeung, Wilson, Parveen, Nazia, Nelson, Michael S, Hart, Ryan, Wang, Shihao, Hsu, Wu Jih, Fueger, Patrick, Kopp, Janel L, Huising, Mark O, Dhawan, Sangeeta, Shih, Hung Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482429/
https://www.ncbi.nlm.nih.gov/pubmed/37610090
http://dx.doi.org/10.7554/eLife.90006