Loss of Ptpmt1 limits mitochondrial utilization of carbohydrates and leads to muscle atrophy and heart failure in tissue-specific knockout mice

While mitochondria in different tissues have distinct preferences for energy sources, they are flexible in utilizing competing substrates for metabolism according to physiological and nutritional circumstances. However, the regulatory mechanisms and significance of metabolic flexibility are not comp...

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Detalles Bibliográficos
Autores principales: Zheng, Hong, Li, Qianjin, Li, Shanhu, Li, Zhiguo, Brotto, Marco, Weiss, Daiana, Prosdocimo, Domenick, Xu, Chunhui, Reddy, Ashruth, Puchowicz, Michelle, Zhao, Xinyang, Weitzmann, M Neale, Jain, Mukesh K, Qu, Cheng-Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482430/
https://www.ncbi.nlm.nih.gov/pubmed/37672386
http://dx.doi.org/10.7554/eLife.86944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482430/
https://www.ncbi.nlm.nih.gov/pubmed/37672386
http://dx.doi.org/10.7554/eLife.86944

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