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Identification of an alternative triglyceride biosynthesis pathway

Triacylglycerols (TAGs) are the main source of stored energy in the body, providing an important substrate pool for mitochondrial beta-oxidation. Imbalances in the amount of TAGs are associated with obesity, cardiac disease and various other pathologies(1,2). In humans, TAGs are synthesized from exc...

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Detalles Bibliográficos
Autores principales: McLelland, Gian-Luca, Lopez-Osias, Marta, Verzijl, Cristy R. C., Ellenbroek, Brecht D., Oliveira, Rafaela A., Boon, Nicolaas J., Dekker, Marleen, van den Hengel, Lisa G., Ali, Rahmen, Janssen, Hans, Song, Ji-Ying, Krimpenfort, Paul, van Zutphen, Tim, Jonker, Johan W., Brummelkamp, Thijn R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482677/
https://www.ncbi.nlm.nih.gov/pubmed/37648867
http://dx.doi.org/10.1038/s41586-023-06497-4